






BIOLabs PRO E3 5.0 Cream
BIOLabs PRO® E3 5.0 Cream is a topical cream packaged in a pump dispenser.
Product Details
• 2 Month Supply
• 5,000 mcg per pump
• Pump-style bottle
• Manufactured in the USA
• Cream-based formula
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
**365 day return in accordance with BIOLabs PRO® published return policy.
- Purified Water
- Vegetable Glycerin
- Aloe Vera Leaf Gel
- Caprylic/Capric Triglyceride
- Stearic Acid
- Microionized Estriol USP
- Olive Oil
- Coconut Oil
- She Butter
- Sunflower Lecithin
- Methylsulfonylmethane (MSM)
- Stearyl Alcohol
- Isopropyl Palmitate
- Allantoin
- Carbomer
- Sodium Bicarbonate
- Herbal-Active® (Natural Preservative)
ESTRIOL
BIOLabs PRO® Est-Riol Cream is a topical cream formulated with bioidentical estriol in a smooth, moisturizing base. Each pump delivers a measured amount of estriol along with skin-conditioning ingredients like aloe vera, MSM, coconut oil, and shea butter. The lightweight formula absorbs easily for convenient daily use.
DIRECTIONS
Step 1: Apply one pump daily to clean skin on areas such as the inner arms, thighs, chest, or inner forearms.
Step 2: Gently massage the cream into the skin until fully absorbed.
Step 3: Allow the cream to fully absorb before covering the area.
FEATURES
• Two-Month Supply
• Each pump delivers 5000 mcg of estriol (E3) in a smooth topical cream.
• Includes MSM, aloe vera, coconut oil, and shea butter.
• Made in the USA in an FDA-inspected facility and paraben-free.
Frequently Asked Questions
Estriol is one of the three main types of estrogen your body produces. It is the weakest estrogen, often called “gentle estrogen.” Estradiol is the strongest and most active during reproductive years, while estrone is weaker and more common after menopause. Estriol provides benefits with less systemic stimulation, making it popular in bioidentical hormone therapy.
Estriol provides gentle, broad estrogen support — helping improve vaginal and urinary health, easing menopause symptoms, protecting bone and skin, and potentially offering a safer long-term profile compared to stronger estrogens.
Estriol binds weakly to estrogen receptors, giving it a milder effect on tissues like the uterus and breast. This gentleness often leads to fewer side effects compared to stronger estrogens like estradiol. Some studies suggest estriol may even block stronger estrogens from over-stimulating cells.
Estriol cream: Primarily tissue-specific; great for localized support like vaginal dryness or skin thinning, with minimal systemic estrogen exposure.
Bi-Est cream: Broader support; can help support hot flashes, mood, energy, skin, bone, and cardiovascular health, while still containing estriol for gentler tissue-specific benefits.
Estriol is typically a milder estrogen option. BIOLabs PRO also offers combination creams incorporating estradiol, progesterone, DHEA, or vitamin D for comprehensive hormone therapy—best suited for individuals with specific clinical recommendations
No—the strength of the cream is the same in both bottles. The 3.6 oz bottle uses a more precise pump mechanism, which allows for smaller, adjustable doses. This design is especially convenient for people who need to take half doses or slightly less, giving you more control over your daily regimen.
For optimal absorption, we recommend applying the cream after a shower, when your skin is clean and your pores are open. This helps maximize hormone delivery and effectiveness.
This cosmetic product contains bioidentical hormones, Estriol and Estradiol, which may affect hormone levels. For external use only.
Consult a qualified healthcare provider before use, especially if you are:
• Pregnant or nursing
• Under 18
• Taking medications
• Managing a hormone-sensitive condition
Stop use and seek medical advice if you experience unusual symptoms such as mood changes, menstrual irregularities, or skin irritation.
Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA.
Keep out of reach of children.