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The age-old question, what comes first? The chicken or the egg?, can be asked about pregnenolone and DHEA. Both pregnenolone and DHEA are precursor hormones that produce other important male and female sex hormones in the body. So the question is pregnenolone the same as DHEA? The answer is yes and no, and here's why.     What is pregnenolone?  Pregnenolone is sometimes nicknamed the grandparent hormone to other steroid hormones. The adrenal glands synthesize cholesterol into pregnenolone. While the adrenal glands produce most of the pregnenolone, the brain, skin, live, testes, and ovaries produce smaller amounts.  After synthesizing, pregnenolone can...

Many people consider balancing their hormones the key to a long and healthy life. One of those necessary hormones is the steroid hormone DHEA or dehydroepiandrosterone. Different options exist to balance hormones, supplementing a DHEA topical cream or tablet is a popular option. For those considering taking DHEA, the question may be, "Does DHEA really work?" The short answer is yes, and here's why. What is DHEA? DHEA is a hormone generated in the adrenal glands. In turn, it's a precursor (foundation) for other essential male and female sex hormones, such as testosterone and estrogen. When DHEA enters the bloodstream,...